Árbol de las Trompetas

…Brugmansia is considered the strongest and most toxic (kepigari) of all the plants in the Matsigenka pharmacopoeia (Shepard, 1998, 2005a). Unlike ayahuasca, which is taken frequently, usually in groups including the healer and / or patient, Brugmansia is taken rarely, usually alone and only by the patient. Frequent use of Brugmansia is considered very dangerous, leading to death or madness. Brugmansia is the last resort, the highest medical authority reserved for the most drastic cases. The shaman, healer or a respected family member prepares the potion and is responsible for watching over the person during the course of intoxication. The potion is prepared with great care, attention and respect. A branch of the plant is broken by hand (it should not be cut with a metal tool, which would offend the spirit of the plant) and a few inches of the pith is scraped out. The scraped material is boiled in water for fifteen minutes or more, or steamed at high temperatures in a banana or other plant leaf. The potion is brewed away from the household to avoid contamination or impurities that could kill the patient. Doses are measured very carefully in drops or small gourds, as even a small dose can last from one night to three days. An overdose can make you hallucinate for weeks or months, go crazy for the rest of your life, or die.

chacruna.net/toe-brugmansia-suaveolens-the-path-of-day-and-night